Temovate® (cream and ointment)

$250.00$800.00

Temovate

Active Ingredient: Clobetasol Propionate

Temovate cream is used to reduce itching, redness, and swelling associated with many skin conditions.

Other names for this medication:
Clobetasol

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Description

TEMOVATE®
(clobetasol propionate cream) Cream, 0.05%
(clobetasol propionate ointment) Ointment, 0.05%

DESCRIPTION

TEMOVATE® (clobetasol propionate cream and ointment) Cream and Ointment, 0.05% contain the active compound clobetasol propionate, a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.

Chemically, clobetasol propionate is (11ß,16ß)-21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1- oxopropoxy)-pregna-1,4-diene-3,20-dione, and it has the following structural formula:

 

TEMOVATE® (clobetasol propionate) Structural Formula Illustration

Clobetasol propionate has the molecular formula C25H32CIFO5 and a molecular weight of 467. It is a white to cream-colored crystalline powder insoluble in water.

TEMOVATE® Cream contains clobetasol propionate 0.5 mg/g in a cream base of propylene glycol, glyceryl monostearate, cetostearyl alcohol, glyceryl stearate, PEG 100 stearate, white wax, chlorocresol, sodium citrate, citric acid monohydrate, and purified water.

TEMOVATE® Ointment contains clobetasol propionate 0.5 mg/g in a base of propylene glycol, sorbitan sesquioleate, and white petrolatum.

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Drug Description

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TEMOVATE®
(clobetasol propionate cream) Cream, 0.05%
(clobetasol propionate ointment) Ointment, 0.05%

DESCRIPTION

TEMOVATE® (clobetasol propionate cream and ointment) Cream and Ointment, 0.05% contain the active compound clobetasol propionate, a synthetic corticosteroid, for topical dermatologic use. Clobetasol, an analog of prednisolone, has a high degree of glucocorticoid activity and a slight degree of mineralocorticoid activity.

Chemically, clobetasol propionate is (11ß,16ß)-21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1- oxopropoxy)-pregna-1,4-diene-3,20-dione, and it has the following structural formula:

 

TEMOVATE® (clobetasol propionate) Structural Formula Illustration

Clobetasol propionate has the molecular formula C25H32CIFO5 and a molecular weight of 467. It is a white to cream-colored crystalline powder insoluble in water.

TEMOVATE® Cream contains clobetasol propionate 0.5 mg/g in a cream base of propylene glycol, glyceryl monostearate, cetostearyl alcohol, glyceryl stearate, PEG 100 stearate, white wax, chlorocresol, sodium citrate, citric acid monohydrate, and purified water.

TEMOVATE® Ointment contains clobetasol propionate 0.5 mg/g in a base of propylene glycol, sorbitan sesquioleate, and white petrolatum.

For Consumers

WHAT ARE THE POSSIBLE SIDE EFFECTS OF CLOBETASOL TOPICAL?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when clobetasol topical is applied to the skin, you should be aware of side effects that can occur if the medication is absorbed into your bloodstream.

Stop using this medication and call your doctor at once if you have severe irritation of any treated skin, or if you show signs of absorbing clobetasol topical through your skin, such as:

  • blurred vision, or…

Indications & Dosage

INDICATIONS

TEMOVATE® Cream and ointment are super-high potency corticos-teroid formulations indicated for the relief of the inflammatory and pru-ritic manifestations of corticosteriod-responsive dermatoses. Treatment beyond 2 consecutive weeks is not recommended, and the total dosage should not exceed 50 g/week because of the potential for the drug to suppress the hypothalamic pituitary adrenal (HPA) axis. Use in pediatric patients under 12 years of age is not recommended.

As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary.

DOSAGE AND ADMINISTRATION

Apply a thin layer of TEMOVATE® Cream or Ointment to the affected skin areas twice daily and rub in gently and completely (see INDICATIONS AND USAGE).

TEMOVATE® Cream and Ointment are super-high potency topical corti-costeroids; therefore, treatment should be limited to 2 consecutive weeks and amounts greater than 50 g/week should not be used.

As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary.

TEMOVATE® Cream and Ointment should not be used with occlusive dressings.

Geriatric Use

In studies where geriatric patients (65 years of age) have been treated with TEMOVATE® Cream or Ointment, safety did not differ from that in younger patients; therefore, no dosage adjustment is recommended.

Additional information

Quantity

30 Grams, 60 Grams, 100 Grams

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